German Qioptiq semiconductor laser assists life science instrument research


German Qioptiq semiconductor laser assists life science instrument research Keywords: semiconductor laser, qioptiq, life science laser

Summary:

With the development of life science instruments such as laser scanning confocal microscopy/flow cytometry, the performance requirements of lasers are getting higher and higher, power stability, noise, spot pointing stability and ease of use are all raised. High requirements, and the German Qioptiq iFLEX series laser is the product for this market.

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How does Qioptiq laser improve the performance of life science instruments?

In life science instruments such as flow cytometry, to improve the performance of the instrument:

1. Hit the focused beam onto a flowing sample that is less than 100 μm wide. In order to get meaningful data from the moving target, it is necessary to ensure that the detector and the light source have very good stability. If either of them moves, it will produce image jitter and reduce resolution.

2. Position the parallel spots of light hitting the flow cells by multiple beams and separate the points to prevent crosstalk in the detector channels.

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Qioptiq uses a single-mode fiber-coupled system to transmit laser light onto the sample for better laser stability, image resolution, and reduced device size and robustness. Qioptiq fiber products offer pointing stability up to 1μrad/°C. And the use of fiber optics makes the layout of the device more flexible, and maintenance does not take a long time to adjust the light path. The Qioptiq fiber coupling system has the following advantages:

1. The beam pointing stability is good;

2. The image resolution is high;

3. Less affected by ambient temperature and physical impact;

4. The equipment produced is small in size and flexible;

5. Due to its very good beam pointing stability and high resolution images, it can be used to screen for smaller organisms for more in-depth research.

The KineFLEX single-mode fiber system from Qioptiq combines the iFLEX series of low-noise-stabilized semiconductor lasers to provide an excellent laser module solution for flow cytometry systems. And KineFLEX-Hydra can couple two or more beams of light into a beam of light to output to the flow cell, and can choose different laser wavelengths according to the fluorescent dye to meet the different needs of flow cytometry.

· Free space - fiber coupling free switching, plug and play, no need to repeat calibration

· High power stability 8 h
· Low noise RMS
· High beam stability · Power adjustable, 0.1-100%

· Integrated spot shaping

Applications:

Four 35mW fiber-coupled semiconductor lasers integrated (405nm, 488 nm, 561 nm, 638 nm) combined output for laser scanning confocal microscopy

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solution:

We have provided laser source solutions for Shanghai Jiaotong University, a research institute of the Chinese Academy of Sciences, Nanjing University, Suzhou Medical Technology Co., Ltd. and many other research units and enterprises. There are two main types:

1) Single wavelength laser combining

iFLEX-iRIS series single-wavelength lasers, through the Adder combiner, and finally output multi-wavelength laser through the fiber;

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iFLEX-iRIS Series Fiber Coupled Lasers + Fiber Combiners iFLEX-AdderTM

2) Multi-wavelength laser

The iFLEX-Gemini series and the iFLEX-Viper series integrate lasers of different wavelengths into the same laser head. By optical coupling, two or more wavelengths of laser light can be simultaneously output, and up to five wavelengths of lasers can be integrated. The wavelength can be switched at will.







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iFLEX-Gemini Dual Wavelength Laser iFLEX-Viper Multiwavelength Laser


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